Lorastyne: Uses, Dosage, Side Effects and Composition

Description and Composition of Lorastyne

Lorastyne is a 2nd generation antihistamine drug used to relieve the symptoms of allergies of different origin.
It contains Loratadine as its active ingredient. It also contains inactive ingredients called excipients in sufficient quantities.
Lorastyne is a potent, rapidly effective and long-acting non-sedative, histamine H, receptor antagonist, with anti-allergic properties.
The above statement means that Lorastyne acts against the production and release of histamine from the body, mast cells particularly.
Histamine is a chemical that brings about allergic signs and symptoms in people. This means that any drug that can stop its production and release will be effective in treating signs and symptoms of allergies.
Lorastyne comes in different dosage forms which includes tablets, capsules, Syrup etc.

 Uses of Lorastyne

Lorastyne is indicated for:
  1. Seasonal allergic rhinitis
  2. Perennial allergic rhinitis
  3. Sneezing, rhinorrhoea & itching
  4. Ocular itching and burning
  5. Chronic urticaria and other allergic dermatologic disorders,

Dosage and administration of Lorastyne

Adults and children above 12 years of age:

  • 10 mg ( tablet of Lorastyne 10mg) once a day.


  • 6 – 12 years : 10 mg ( tablet of Lorastyne 10mg) once a day
  • 2-5 years: 5 mg or 5 ml of 5 mg/ 5ml Loratadine syrup) once a day.
Safety and efficacy of Lorastyne in children below 2 years of age have not yet been established.

Contraindications of Lorastyne

It is contraindicated in patients who have hypersensitivity or idiosyncrasy to its component

Use of Lorastyne in Special Populations 

  • Neonates: Lorastyne is not normally used in neonates.
  • Children: The safety and efficacy of Loratadine in children below 2 years of age have not yet been established

Lorastyne use in pregnancy and lactation 

It should be used only if the potential benefit justifies the potential risk to fetus or infant.

Drug interactions with Lorastyne

There are no reports of potentially hazardous interactions with other drugs.
Psychomotor performance studies show that unlike other H, receptor antagonists, Loratadine does not potentiate the effect of alcohol when administered concomitantly with it.

Side Effects of Lorastyne  

The following are some side effects associated with Lorastyne:

  • Rash
  • hives
  • itching
  • swelling in some areas (like: eyes, face, lips, tongue, throat, hands, arms, feet, ankles or lower legs),
  • hoarseness,
  • difficulty in breathing or swallowing, wheezing.

Please note that you may experience just few of the side effects or none of them at all.

You may equally experience other side effects of Loratadine other than those enlisted above.

Please report any serious or life-threatening side effect of any medication to your doctor immediately you experience it.

Precautions to take while taking Lorastyne 

Precaution is needed in patients with kidney or liver diseases, people with certain allergies and women who are pregnant or breast feeding.


Keep in a dry place, below 30°C. Protect from light. Keep out of the reach of children.


  1. Pubchem
  2. NHS
  3. Medline Plus
  4. Loratadine drug information

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